Reduction in peripheral regulatory T cell population in childhood ocular type myasthenia gravis
نویسندگان
چکیده
منابع مشابه
Thymectomy in Patients with Myasthenia Gravis
A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative preparation, anesthetic and surgical management is -discussed.
متن کاملOcular Manifestations of Myasthenia Gravis
The cause of the weakness is due to a defect at the level of the neuromuscular junction in which autoimmune antibodies block the receptors responsible for initiating muscular contraction. The neurotransmitter that is subject to this competitive inhibition is acetylcholine (ACh). The muscles commonly affected include those of the neck, limbs and chest cavity with regards to breathing. The muscle...
متن کاملOcular Neuromyotonia and Myasthenia Gravis.
To the Editors: Myasthenia gravis presents with only ocular symptoms (diplopia, ptosis, and extraocular movement limitation) in approximately 20% of patients.1,2 Ocular myasthenia gravis is to be suspected in patients with intermittent diplopia with ophthalmoplegia that does not correspond to a single ocular motor nerve paresis. However, diplopia in only eccentric sustained gaze in myasthenia g...
متن کاملUp-regulated expression of Fas antigen in peripheral T cell subsets in patients with myasthenia gravis.
PURPOSE Recent reports have linked various autoimmune diseases to defective Fas-mediated apoptosis or Fas expression. Here we aimed to determine whether Fas-mediated apoptosis is involved in the pathogenesis of myasthenia gravis (MG). METHODS The expression of Fas antigen in peripheral T cell subsets from 17 Chinese patients with MG and 13 healthy individuals was determined by flow cytometry,...
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ژورنال
عنوان ژورنال: Brain and Development
سال: 2015
ISSN: 0387-7604
DOI: 10.1016/j.braindev.2014.12.007